As a unisex name, it can be used as 類, 流生, 流衣, 琉以, 琉依, 琉唯, 琉生, 琉衣, 瑠伊 or 瑠依 with 類 (rui, tagu.i) meaning "class, genus, kind, sort, variety", 流 (ryuu, ru, naga.re) meaning "a sink, current, flow, forfeit", 生 (shou, sei, i.kiru, i.keru, -u, u.mare, o.u, ki, na.ru, ha.eru) meaning "birth, genuine, life", 衣 (i, e, kinu, -gi, koromo) meaning "clothes, dressing, garment", 琉 (ryuu, ru) meaning "gem, lapis lazuli, precious stone", 以 (i, mo'.te) meaning "because, by means of, compared with, in view of", 依 (i, e, yo.ru) meaning "consequently, depend on, due to, reliant, therefore", 唯 (i, yui, tada) meaning "merely, only, simply, solely", 瑠 (ryuu, ru) meaning "lapis lazuli" and 伊 (i, kare) meaning "Italy, that one."
As a masculine name, it can be used as 塁, 流維, 琉偉, 琉威 or 琉維 with 塁 (sui, rai, rui, toride) meaning "base(ball), bases, fort, rampart, walls", 維 (i) meaning "fibre, rope, tie", 偉 (i, era.i) meaning "admirable, conceited, excellent, famous, greatness, remarkable" and 威 (i, odo.kasu, odo.shi, odo.su) meaning "dignity, intimidate, majesty, menace, threaten."
As a feminine name, it can be used as either 流依 or 瑠以.