Argentine Presidents: 1 president
Manuel Quintana   1904-1906  
Brazilian Presidents: 2 presidents
Deodoro da Fonseca (a.k.a. Manuel)   1889-1891  
Manuel Ferraz de Campos Sales   1898-1902  
Fictional Characters from Television: 1 character
Manny Devalos   2005   Medium  
French Presidents and Prime Ministers: 1 prime minister
(prime minister) Manuel Valls   2014-2016  
Nobel Prize Winners: 1 peace
(peace) Juan Manuel Santos   2016  
Notable Actors and Entertainers: 1 actor
Jay Hernandez (middle name Manuel)   1978-  
Notable Athletes: 7 soccer, 2 basketball, 1 driving, 1 rugby, 1 tennis
(driving) Juan Manuel Fangio   1911-1995  
(soccer) Garrincha (a.k.a. Manuel)   1933-1983  
(tennis) Manuel Santana   1938-2021  
(basketball) Lolo Sainz   1940-  
(basketball) José Calderón (middle name Manuel)   1981-  
(soccer) Hélder Postiga (middle name Manuel)   1982-  
(soccer) Pepe Reina (middle name Manuel)   1982-  
(rugby) Juan Manuel Leguizamón   1983-  
(soccer) Silvestre Varela (middle name Manuel)   1985-  
(soccer) Manuel Neuer   1986-  
(soccer) Nolito (a.k.a. Manuel)   1986-  
(soccer) Juan Mata (middle name Manuel)   1988-  
Notable Musicians: 3 singers, 1 composer, 1 musician
Isaac Albéniz (middle name Manuel)   1860-1909  
Bobby Capó (middle name Manuel)   1922-1989  
Manny Charlton   1941-2022  
Nino Bravo (middle name Manuel)   1944-1973  
Manuel Turizo   2000-  
Olympic Medalists: 6 bronze, 5 silver, 1 gold, 1 silver/bronze, 1 silver/gold
(silver) Manuel Plaza   1928   marathon  
(bronze) Manuel dos Santos   1960   swimming - 100 m freestyle  
(bronze) José Manuel Abascal   1984   1500 m  
(silver) Juanma López Iturriaga (middle name Manuel)   1984   basketball  
(silver) José Manuel Beirán   1984   basketball  
(silver) Fernando Romay (middle name Manuel)   1984   basketball  
(silver/gold) Manuel Estiarte   1992; 1996   water polo  
(silver) Manuel Silvestre Sánchez   1992   water polo  
(bronze) Manuel Martínez   2004   shot put  
(gold) Manuel Vega   2004   baseball  
(bronze) Rui Silva (middle name Manuel)   2004   1500 m  
(bronze) Manuel Štrlek   2012   handball  
(silver/bronze) José Calderón (middle name Manuel)   2008; 2012; 2016   basketball  
(bronze) Jairo Asencio (middle name Manuel)   2020   baseball  
Other Leaders: 3 presidents, 1 leader
President Manuel L. Quezon   1935-1944   Philippines  
President Manuel Roxas   1946-1948   Philippines  
President Manuel Urrutia Lleó   1959   Cuba  
Leader Manuel Noriega   1983-1989   Panama  
Portuguese Kings and Queens: 2 kings
King Manuel I the Fortunate   1495-1521  
King Manuel II   1908-1910  
Portuguese Presidents and Prime Ministers: 2 presidents, 2 prime ministers, 1 prime minister/president
(president) Manuel de Arriaga   1911-1915  
(prime minister) Manuel Maria Coelho   1921  
(president) Manuel Teixeira Gomes   1923-1925  
(prime minister/president) Manuel Gomes da Costa   1926  
(prime minister) José Manuel Barroso   2002-2004  
Roman and Byzantine Emperors: 2 emperors
Emperor Manuel Comnenus   1143-1180  
Emperor Manuel Palaeologus   1391-1425  
Saints: 3 blessed, 2 saints
Blessed Emmanuel Ruiz López (a.k.a. Manuel)   1804-1860  
Saint Faustino Miguez (a.k.a. Manuel)   1831-1925  
Blessed Manuel Domingo y Sol   1836-1909  
Saint Manuel González García   1877-1940  
Blessed Carlos Manuel Rodríguez Santiago   1918-1963  
Spanish Prime Ministers: 5 prime ministers
Manuel Ruiz Zorrilla   1871; 1872-1873  
Manuel García Prieto   1917; 1917-1918; 1918; 1922-1923  
Manuel Allendesalazar   1919-1920; 1921  
Manuel Portela Valladares   1935-1936  
Manuel Azaña   1931-1933; 1936