50%RatingSave Gender Feminine Usage Spanish Pronounced Pron. /de.sam.pa.ˈɾa.ðos/ [key·simplify] Meaning & History Means "helpless, defenceless, forsaken" in Spanish. It is taken from an epithet of the Virgin Mary, Nuestra Señora de los Desamparados, meaning "Our Lady of the Helpless". She is the patron saint of Valencia, Spain. PopularityDetails Last ranked #321 in 1960 Spain (by decade) Categories Marian titles, negative, patron saints, solitary, Spanish words