Namesakes
American Presidents:
1 president
Harry S. Truman (middle name S) 1945-1953 
Fictional Characters from Television:
2 characters
Harry Solomon (middle name S) 1996 3rd Rock from the Sun
George S. Hammond (middle name S) 1997 Stargate SG-1
Notable Writers:
1 author
C. S. Friedman (middle name S) 1957-