Namesakes
American First Ladies:
1 first lady
Louisa Adams 1825-1829 
Fictional Characters from Books:
2 characters
Louisa Musgrove 1818 Persuasion
Louisa Gradgrind 1854 Hard Times
Notable Actors and Entertainers:
5 actors, 1 actor/comedian
Renée Adorée (middle name Louisa) 1897-1933
Valerie Hobson (middle name Louisa) 1917-1998
Anne Bancroft (middle name Louisa) 1931-2005
Wieteke van Dort (a.k.a. Louisa) 1943-2024
Jean Louisa Kelly 1972-
Rebecca Ferguson (middle name Louisa) 1983-
Notable Writers:
1 author
Louisa May Alcott 1832-1888
Oscar Award Winners:
1 actress
(actress) Anne Bancroft (middle name Louisa) 1963 The Miracle Worker
Other Royalty:
2 princesses, 1 princess/empress consort/queen consort, 1 princess/queen consort, 1 queen consort
Luise Ulrike of Prussia (a.k.a. Louisa) 1720-1782; 1751-1771 Prussia; Sweden
Marianne of the Netherlands (middle name Louisa) 1815-1883 Netherlands
Wilhelmine of Prussia (middle name Louisa) 1815-1837 Netherlands
Louise, Duchess of Argyll (a.k.a. Louisa) 1848-1939 United Kingdom
Victoria, Princess Royal (middle name Louisa) 1840-1901; 1888 United Kingdom; German Empire; Prussia
Saints:
2 blessed
Blessed Louise of Savoy (a.k.a. Louisa) 1461-1503
Blessed Ludovica Albertoni (a.k.a. Louisa) 1473-1533
Tony Award Winners:
1 actress
(actress) Anne Bancroft (middle name Louisa) 1960 The Miracle Worker