Save Gender Feminine Usage Popular Culture, English (American, Rare) Pronounced Pron. /ˈhɑɹ.li ˈkwɪn/(American English) [key·simplify] Other Forms FormsHarley Quinn Meaning & History Combination of Harley and Quinn. Harley Quinn is a fictional character in comic books by DC Comics and was one of the main characters in the 2016 movie 'Suicide Squad'. She was portrayed by Australian actress and film producer, Margot Robbie.