Save Gender Feminine Usage History Pronounced Pron. zan-TIP-ə(English) [key] Meaning & History Latinate form of Xanthippe. Saint Xantippa or Xanthippe and her sister Saint Polyxena were Spanish martyrs of the 1st century. The apocryphal Acts of Xanthippe and Polyxena is a 3rd- or 4th-century account of their lives.