80%RatingSave Gender Masculine Usage Cherokee Scripts ᏍᏏᏉᏯ, ᏎᏉᏯ(Cherokee) Meaning & History Probably derived from Cherokee ᏏᏆ (siqua) meaning "hog". This was the name of the Cherokee man (also known as George Guess) who devised the Cherokee writing system in the 19th century. Categories animals, fauna, history, nature, uncertain etymology