María Manuela

Dona Maria Manuela (1527 – 1545) was the eldest daughter and second child of King John III of Portugal and his wife Catherine of Austria. She was Princess of Asturias and Duchess of Milan as the first wife of the future Philip II of Spain, and Princess of Portugal as heir presumptive to the Portuguese throne between 1527 and 1535.

Doña María Manuela Kirkpatrick de Grevignée, Countess of Montijo (1794 – 1879), was a Spanish noble and courtier, the mother of Eugénie, Empress of the French. She served as Camarera mayor de Palacio to queen Isabella II of Spain in 1847-1848.