A female Chamorro name, either derived from the noun isa meaning "rainbow", or possibly derived from the verb meaning "to flatter" or the transitive verb meaning "to rise, to haul up".
From the germanic element is "Ice" with the feminine suffix -a. In Swedish the name literally means ice in verbal form. Which means that something has frozen solid or has been covered in ice. It can also be a short for of names that end in -isa. Like Lovisa, Lisa or Disa.