Gregoria Apaza (1751– 1782), was an Aymara (indigenous Bolivian) leader. In 1781, she participated with her brother Julian Apaza (Tupac Katari) and sister-in-law Bartolina Sisa in a major indigenous revolt against Spanish colonial rule in Bolivia. These Aymara leaders laid siege to the cities of La Paz and Sorata before being defeated and executed.
Gregoria (Greek: Γρηγορία, fl. 641) was the Byzantine empress as the wife of Constantine III. She participated in the minor regency government of her son, Constans II, in 641–650.