Save Gender Masculine Usage French Pronounced Pron. /fʁɑ̃.swa ʁe.ʒis/ [key·simplify] Meaning & History Combination of François and Régis. It is used in honor of Saint Jean-François Régis (1597-1640), who is known as John Francis Regis in English.In France, the name's name day is June 16th, which is also the feast day of John Francis Regis.