100%RatingSave Gender Masculine Usage Spanish Pronounced Pron. /e.ˈfɾen/ [key·simplify] Meaning & HistoryExpand Links Spanish form of Ephraim (referring to Saint Ephrem the Syrian). Related NamesFamily Tree·Details VariantEfraínOther Languages & CulturesEphraim(Biblical) Ephraim(Biblical Greek) 'Efrayim(Biblical Hebrew) Ephraim(Biblical Latin) Efraim, Ephraim(Hebrew) Efrem, Yefrem(Russian) Jevrem(Serbian) User SubmissionEfren PopularityDetails Last ranked #338 in 2010 Spain (by decade) Last ranked #977 in 2007 United States Name DaysName Days? Spain: June 9