59%RatingSave Gender Masculine Usage English Pronounced Pron. /də.ˈweɪn/, /ˈdweɪn/ [key·simplify] Meaning & HistoryExpand Links Variant of Duane, with the spelling altered due to the influence of Wayne. It can be spelled Dewayne or with a capitalized third letter as DeWayne. Related NamesFamily Tree·Details VariantsDuane, Dwain, DwayneFeminine FormDuana PopularityDetails Last ranked #996 in 2001 United States People think this name isRate·Details modern youthful common urban strong strange complex serious Categories NASCAR, NBA players, P-Funk members, rappers