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Too complicated and nerdy. I can’t picture someone being named either.

Not a fan of either.

They both just look like medications or diseases to me, mostly colitis and the -anus ending just make me think medical.

Coriolanus looks like a place-name used as a name for a man associated with it: think Scipio Africanus. And also think "Brush Up Your Shakespeare" by Cole Porter; absolutely brilliant, but when it comes to "If she says your behavior is heinous, Kick her right in the Coriolanus" perhaps not the kind of association one might want for a fn.

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Coriolana probably wouldn't work in Latin if as I suspect Coriolanus is a place-name epithet. In English, it's close to Coralie, which I like very much indeed.

Coriolanus is a play I saw when I was much too young (and not proficient enough in English) to appreciate it. It seems very much a one-man name.
Coriolana seems very forced as a feminisation. One of these "we really wanted a son" names.