I haven't run into anyone with this particular name, but both "nobu" and "-suke" are common elements in Japanese names ("nobu" in both male and female names; "-suke" as a suffix for male names only). These elements can be written with a variety of Chinese characters, so you can't give just one meaning for either unless you know exactly how an individual writes his or her name. Meanings given on this site and others should only be taken as possibilities.
For example, a woman I know is named Nobuyo 延世 , after her father Nobuya 延也 . In this case, the character "
Nobu" means "extend, prolong." "Trust, truth" is another meaning for "
Nobu" (信), and there are others.
The suffix "-suke" is often written 助, 祐 or 輔 ("help"), but can also be 介 ("concerned with") and others.
As far as I know,
Nobu is not used as an address, nor does it have any meaning on its own other than "knob" (as an English loanword).