The name became regularly used in the Christian world due to the fame of Saint Anthony the Great, a 4th-century Egyptian hermit who founded Christian monasticism. Its popularity was reinforced in the Middle Ages by the 13th-century Saint Anthony of Padua, the patron saint of Portugal. It has been commonly (but incorrectly) associated with Greek ἄνθος (anthos) meaning "flower", which resulted in the addition of the h to this spelling in the 17th century.
In the medieval legend of Tristan and Iseult this was the name of a king of Cornwall. It was also borne by the American author Mark Twain (1835-1910), real name Samuel Clemens, the author of The Adventures of Tom Sawyer and Adventures of Huckleberry Finn. He took his pen name from a call used by riverboat workers on the Mississippi River to indicate a depth of two fathoms. This is also the usual English spelling of the name of the 1st-century BC Roman triumvir Marcus Antonius (Mark Antony).
Famous bearers include the German intellectual Max Weber (1864-1920) and the German physicist Max Planck (1858-1947). This name is also borne by the title character in the Mad Max series of movies, starting 1979.