In the United States it became more common for girls in the early 1980s, shortly after the debut of the television sitcom The Facts of Life (1979-1988), which featured a character named Blair Warner. The name left the American top 1000 rankings two decades later, but was resurrected by another television character, this time Blair Waldorf from the series Gossip Girl (2007-2012).
This name can also be given in reference to the city in Italy, as in the case of Florence Nightingale (1820-1910), who was born there to British parents. She was a nurse in military hospitals during the Crimean War and is usually considered the founder of modern nursing.