The name has been very common throughout the English-speaking world since end of the 20th century. In the United States it reached a high point in 2017, when it ranked as the fifth most popular name for boys.
Due to the saint's renown, the name became common in the Christian world (in various spellings). As an English name, Luke has been in use since the 12th century alongside the Latin form Lucas. Both forms became popular throughout the English-speaking world towards the end of the 20th century. A famous fictional bearer was the hero Luke Skywalker from the Star Wars movies, beginning in 1977.
As a given name, it took off in popularity during the 1990s. It has been more common for girls in the United States probably because of its similarity to other names such as Megan, Morgan and Regan.