This name was very popular in the English-speaking world at the end of the 19th century. Though it declined in use over the next 100 years, it staged a successful comeback at the end of the 20th century. The American sitcom Will and Grace (1998-2006) may have helped, though the name was already strongly rising when it premiered. It was the top name for girls in England and Wales in 2006.
Due to the renown of the saint, this name became widespread in Western Europe during the Middle Ages. However, it was not regularly used in Britain until the 16th century. Famous bearers include Saint Francis Xavier (1506-1552), a missionary to East Asia, the philosopher and scientist Francis Bacon (1561-1626), the explorer and admiral Francis Drake (1540-1595), and Pope Francis (1936-).
In the English-speaking world this name is occasionally used for girls, as a variant of the homophone Frances.