This name can also be given in reference to the city in Italy, as in the case of Florence Nightingale (1820-1910), who was born there to British parents. She was a nurse in military hospitals during the Crimean War and is usually considered the founder of modern nursing.
This name was not particularly common in Western Europe during the Middle Ages. It became more popular in part due to the fame of Prince Eugene of Savoy (1663-1736), a French-born general who served the Austrian Empire. A notable bearer was the American playwright Eugene O'Neill (1888-1953).