It has occasionally been used as an English given name since the 16th century. It was moderately popular in the 1940s, but had a more notable upswing in the early 2000s. This may have been inspired by the Spanish actress Penélope Cruz (1974-), who gained prominence in English-language movies at that time. It was already rapidly rising when celebrities Kourtney Kardashian and Scott Disick gave it to their baby daughter in 2012.
A famous bearer was the American jazz musician Nina Simone (1933-2003).
In England the name became rare after the Middle Ages, but it was revived in the 19th century, more commonly in the spelling Beatrice. Famous bearers include the British author and illustrator Beatrix Potter (1866-1943), the creator of Peter Rabbit, and Queen Beatrix of the Netherlands (1938-).
The name was borne by a 17th-century English queen and also by the second wife of Henry VIII, Anne Boleyn (the mother of Queen Elizabeth I), who was eventually beheaded in the Tower of London. Another notable bearer was the German-Jewish diarist Anne (Annelies) Frank, a young victim of the Holocaust in 1945. This is also the name of the heroine in the 1908 novel Anne of Green Gables by Canadian author L. M. Montgomery.
In England, this Latin form has been used alongside the vernacular forms Ann and Anne since the late Middle Ages. Anna is currently the most common of these spellings in all English-speaking countries (since the 1970s), however the biblical form Hannah is presently more popular than all three.
The name was borne by several Russian royals, including an 18th-century empress of Russia. It is also the name of the main character in Leo Tolstoy's novel Anna Karenina (1877), about a married aristocrat who begins an ultimately tragic relationship with Count Vronsky.
As an English name it was highly popular from the Middle Ages until the 17th century. It was revived in the 19th century and was common into the 20th, but it fell into decline after the 1930s. It last appeared on the American top 1000 rankings in 1972.