It has been common as a given name in the English-speaking world only since the 18th century. A famous modern bearer is American actress Julia Roberts (1967-).
In the United States this form was much less common than Isabel until the early 1990s, when it began rapidly rising in popularity. It reached a peak in 2009 and 2010, when it was the most popular name for girls in America, an astounding rise over only 20 years.
A famous bearer is the Italian actress Isabella Rossellini (1952-).
Due to the popularity of the saint, the name became common in the Christian world during the Middle Ages. The Normans brought it to England, where it was commonly spelled Cecily — the Latinate form Cecilia came into use in the 18th century.