Que

Meaning uncertain. This name may possibly be a short form of any feminine given name containing -que-, such as Quentina and Jacqueline.

Alternatively, it could also be a more phonetical English spelling of the letter 'q', created by parents who were interested in one-letter names (as instances do exist where a letter is someone's legal name, though usually this is the middle name; a famous example of this was the American president Harry S. Truman).