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Myles Nazem Amine (born in 1996) is a Sammarinese-American freestyle and folkstyle wrestler who competes at 86 kilograms. In freestyle, Amine won bronze for San Marino at the 2020 Summer Olympics and claimed medals at the European Games and the European Championships. He won the gold medal in the 86 kg event at the 2022 Mediterranean Games held in Oran, Algeria. He competed in the 86 kg event at the 2022 World Wrestling Championships held in Belgrade, Serbia. In 2023 he won a bronze medal at the World Championships, a silver medal at the European Championships and a gold medal at Grand Prix. His paternal grandfather Nazem Amine was also a freestyle wrestler who competed for Lebanon at the 1960 Summer Olympics. He will represent San Marino at the 2024 Summer Olympics in Paris. He represents San Marino through his citizenship that was passed through his maternal great-grandparents, Germano and Pierina Mularoni.

Myles Kennedy is the lead vocalist of the rock band Alter Bridge.

Myles Standish (1584-1656) of Plymouth Colony, Massachusetts.

Myles na gCopaleen was one of the pen names of the famous Irish writer Brian Ó Nualláin, also known as Flann O'Brien.