Save Gender Feminine Usage Japanese Scripts 美佐子, 美沙子, 美咲子, 海沙子, etc.(Japanese Kanji) みさこ(Japanese Hiragana) Pronounced Pron. /mʲi.sä.ko̞/ [key·simplify] Meaning & History From Japanese 美 (mi) meaning "beautiful" or 海 (mi) meaning "sea, ocean" combined with 佐 (sa) meaning "help, aid", 沙 (sa) meaning "sand" or 咲 (sa) meaning "blossom" and 子 (ko) meaning "child". Other kanji combinations can form this name as well.