Jules Vaughn is a character in the HBO series Euphoria. She is portrayed by actress Hunter Schafer. Her character is openly transgender, and is shown to have an incredibly strained relationship with her mother due to the latter sending her to a psychiatric hospital as a child. Jules’ story was a collaborative effort between the show’s creator as well as Schafer, who is transgender herself.
― Anonymous User 3/3/2022
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Jules is the nickname of Detective Juliet O'Hara on the TV series Psych.
― Anonymous User 5/2/2021
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Jules McQuin is a Character in Loot and Sting by Jude Watson.
I don't know if this counts as a famous bearer, but the Beatles song Hey Jude was supposed to be Hey Jules, after John Lennon's son Julian. However, Mccartney thought Hey Jules was going to be too hard to sing, so they changed to Hey Jude.