Namesakes
Lupe Vélez
(f) 1908-1944 
Notable Actors and Entertainers (actor)
Lupe Ontiveros
(f) 1942-2012
Notable Actors and Entertainers (actor)
María Guadalupe García Zavala
(f) 1878-1963
Saints
María Lupita González Romero
(f) 1989-
Olympic Medalists 2016 20 km walk (silver)