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Where I live, Louis and Louie are pronounced the same way. I prefer the Louis spelling, because the E spelling looks strange with so many vowels next to each other, and also looks a lot more childish to me.

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However, it depends where you live because if the popular pronounciation of Louis is like Lewis, then this might cause complications if you were pronouncing it like Louie as you'd have to correct people all the time.

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