I'm a little bit biased (it's one of my middle names and a long-standing family name), but I love
Irene! There's something about it that I think works on both a cute little girl and a professional, independent older woman. I've considered using it as a first name myself.
Irene AgathaIrene AlexandraIrene ArtemisiaIrene HelenaIrene MelissaIrene RoxanaIrene SophiaIrene Theodora