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I don't think Thames would be mad in England; for starters, it's a surname, so if I saw it as a middle name in a BA here, I'd assume that's what it was. And even as just a name in its own right, I think it's okay. I'm not really a fan of place-names, but for some reason, I don't mind river-names at all, especially if it's a local river or one there's some family connection to. Samuel Thames sounds fine to me.