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Sanderson means son of Alexander - it seems to have originated in County Durham, England in the early 13th century. A possible ancestor is Alexander de Bedick whose son James took the name James de debick Sanderson (or James de bedick Alexander's son).
Are you researching the Sanderson family?

"Sanderson" literally means "son of Sander". "Sander" is a pet form of "Alexander", which means "helper of mankind."

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-- Nanaea